Choline dendrimers as generic scaffolds for the non-covalent synthesis of multivalent protein assemblies.
نویسندگان
چکیده
A modular self-assembly strategy is presented that allows the non-covalent synthesis of multivalent protein dendrimers using the strong interaction between choline-functionalized dendrimers and the choline binding protein C-LytA. Choline dendrimers displaying fusion proteins of C-LytA and the collagen binding protein CNA35 represent attractive multivalent targeting ligands for collagen imaging.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 21 شماره
صفحات -
تاریخ انتشار 2011